
Cracking of Molded Components
An injection molded component in a consumer product was found to have an increased failure rate over a three-month period.
Home » Frequently Asked Questions About In Vitro Irritation and Cytotoxicity Testing
Biocompatibility assessments are a battery of tests performed to evaluate a product, medical device, or other material for the risk of biological hazards. The first test performed is typically a cytotoxicity evaluation. This is done by preparing an extract of the sample to treat a monolayer of healthy mammalian cells in vitro. Results of this assay can indicate the potential toxicity risk a product carries without testing on animals.
Irritation is a localized non-specific inflammatory response to a single, repeated, or continuous application of a substance or material. The in vitro irritation test involves an extraction in physiologically relevant solvents. These extracts are applied to a reconstructed human epidermis model which contains the major layers of cells that are found in a true human epidermis. Death of the cells in this model after exposure to the extracts collected from a product indicate that an irritating substance was leached off the material and poses a risk of adverse reactions in the end user.
An injection molded component in a consumer product was found to have an increased failure rate over a three-month period.
In this webinar we will focus on Rutherford Backscattering Spectrometry (RBS) which is a thin film analysis technique
EAG’s material and microelectronic testing service is dedicated to providing the best information from ensuring the purity of starting materials, to prototype testing of devices in the ramp up towards full-scale production.
In this webinar we will introduce the principles of Transmission Electron Microscopy (TEM) with a focus on real-world problem-solving.
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