
Exploring the Capabilities of Dual-Beam FIB-SEM
The dual-beam FIB – SEM is an advanced tool that combines precise sample milling/preparation with high-resolution imaging.
Home » Principles and Strengths of In Vitro Testing
In vitro is the Latin term for “in glass,” meaning that the testing is performed in a container that is outside of a living organism. This testing uses cell-based biological models instead of animals or humans. In vitro efforts help fulfil the FDA’s “3Rs approach” to replace, reduce, and/or refine animal testing.
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In Vitro model systems can be specified to the test sample’s intended use. 2D cell cultures are grown rapidly for high-throughput or multi-sample analysis with minimized variation between treatments. Cell cultures can also be made into 3D tissue models. These models contain differentiated cell layers to physiologically represent complex tissues and evaluate specific endpoints. Using specific geometries, in vitro cell culture models can be used to evaluate simple and complex biological responses.
To assess different biological endpoints, various forms of analytical methods may be implemented. Measurable responses of the in vitro models include cell death, growth inhibition, genetic alterations, changes in surface marker expression and altered metabolism.
The dual-beam FIB – SEM is an advanced tool that combines precise sample milling/preparation with high-resolution imaging.
Cryo TEM involves performing TEM analysis while keeping the sample at cryogenic temperatures, around -170°C.
During this Ask the Expert webinar, our team of battery materials experts will address your pre-submitted questions during the event, as well as present about our new battery lab’s capabilities.
LA-ICP-MS is a technique that uses direct micro-scale sampling to provide high precision elemental characterization of solid materials.
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